HALOTHANT 전신마취후 발생한 독성간염
A case report of halothane induced toxic hepatitis
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백운봉
윤규호/노영성/박성원/신명상/허남오
KMID : 0360119940160030315
Abstract
General anesthesia is necessary to operation in dept. of oral and maxillofacial surgery. Halothane is one of the most commonly used anesthetic agent for general anesthesia because of its property of nonexplosive, inexpensive, strong activeness
and
chemical stability. Halothane is fluorinated hydrocarbone anesthetic agent and structurally similar to chloroform.
On the contrary halothane has been reported to result in severe hepaitc necrosis in a small number of individuals.
Although the mechanism of halothane induced toxic hapatitis is unclear, it appears to be closely related to reducting metabolite, reactant intermediate product, immune reaction, hypersensitivity and so on.
This is a case report of 27 years old male patient occured halothane induced hepatitis following ofter operation of mandible fracture.
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